HCID 10850551, compound → HCID 135536693, compound

HRID 326862Notes

Reaction equation

HRID 326862 reaction equation
N[C:2]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][N:10]=2)[N:5]=[C:4]([CH2:12][S:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:3]=1.C([OH:23])C.CN(C)C=O>[OH-].[Na+]>[CH2:14]([S:13][CH2:12][C:4]1[NH:3][C:2](=[O:23])[C:11]2[C:6](=[N:7][CH:8]=[CH:9][N:10]=2)[N:5]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 10850551HCID 10850551, compoundHCID 19794673N,N-dimethylformamide ethanol

Product 1

HCID 135536693HCID 135536693, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Obtained using the procedure described in section b of Example 9, starting with 5.4 g (0.019 mole) of 4-amino-2-(benzylthiomethyl)pteridine in 400 ml of 5% aqueous sodium hydroxide. Reaction time: 7 hours at 85° C. Yld: 1.7 g (31%), m.p. 224°-226° C. (ethanol/N,N-dimethylformamide).

Workup

  1. customObtained
  2. customReaction time
  3. custom7 hours
  4. customat 85° C

Sources & evidence

ORD record
ord-00f4e5f422e0456fba690aeb591be7a3
Source dataset
uspto-grants-1993_12
Patent number
US05270465

Reaction notes

Loading…