HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 3-(2-(7-Chloroquinolin-2-yl)vinyl)benzaldehyde | HCID 53394853 | — |
| Reactant | HCID 178418689 | HCID 178418689 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)ethanone | HCID 54221497 | — |
Reaction Steps
To 3-(2-(7-chloro-2-quinolinyl)ethenyl)benzaldehyde, MeMgBr was added (in THF at 0° C.) to give an ethanol derivative, which was oxidized to the title compound as in Example 15, Step 11. 1H NMR (CD3COCD3): δ 2.68 (3H, s), 7.55-7.68 (3H, m), 7.89-8.05 (6H, m), 8.36 (2H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270324 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-1e286c38d9804e629bee765edd25d5fb |
| Source note | uspto-grants-1993_12 |