(2-Thienylmethyl)amine → HCID 19734532, compound

Participants

Reaction Steps

Methyl N-cyano-2-pyridinecarboximidate (0.50 g, 3.1 mmol) was dissolved in methanol (10 ml), 2-thiophenemethylamine (0.38 g, 3.4 mmol) was added, and the resulting mixture was stirred at room temperature for 40 minutes. After the reaction was completed, the reaction solution was . concentrated under reduced pressure, and the residue thus obtained was crystallized from dichloromethane diethyl ether to give the title compound (0.40 g, 1.7 mmol, yield: 54%) as colorless needles.

Provenance & Evidence