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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327252Generated: October 30, 2026

Allyl bromide → 3-[N-Allyl-3-(4-chlorobenzyl)-6-(quinolin-2-ylmethoxy)-indol-2-yl]-2,2-dimethylpropanoic acid

https://huagongshe.com/reaction/327252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAllyl bromideHCID 7841—
ReactantMethyl 3-[N-(phenylsulfonyl)-3-(4-chlorobenzyl)-6-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoateHCID 18947579—
Product3-[N-Allyl-3-(4-chlorobenzyl)-6-(quinolin-2-ylmethoxy)-indol-2-yl]-2,2-dimethylpropanoic acidHCID 18947555—

Reaction Steps

The title compound was prepared under the conditions described in Step A and Step B of Example 38, but substituting allyl bromide for the benzenesulfonyl chloride from Example 38 (Step A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05272145
Source datasetuspto-grants-1993_12
ORD IDord-68bb106446fa490eab9163da18952d8f
Source noteuspto-grants-1993_12