HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Oxide → rel-(4R,5S)-4,5-bis(3'-Benzyloxy-4'-methoxyphenyl)-3-(2'-hydroxyethyl)oxazolidine-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Oxide | HCID 6354 | — |
| Reactant | Methanamine, hydrochloride (1:1) | HCID 11637 | — |
| Reactant | rel-(4R,5S)-4,5-bis(3'-benzyloxy-4'-methoxyphenyl)oxazolidin-2-one | HCID 15011034 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | rel-(4R,5S)-4,5-bis(3'-Benzyloxy-4'-methoxyphenyl)-3-(2'-hydroxyethyl)oxazolidine-2-one | HCID 15011035 | — |
Reaction Steps
Mixture: 100 mg of rel-(4R,5S)-4,5-bis(3'-benzyloxy-4'-methoxyphenyl)oxazolidin-2-one, 5 ml of ethylene oxide, 15 ml of tetrahydrofuran, 5 mg of methylammonium chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05272270 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-de698e6da9e241918f4e5e07888b6435 |
| Source note | uspto-grants-1993_12 |