HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,5-Difluorophenyl)pentan-1-ol → 1,3-Difluoro-5-(pent-1-en-1-yl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,5-Difluorophenyl)pentan-1-ol | HCID 22598443 | — |
| Reactant | HCID 178526999 | HCID 178526999 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | 1,3-Difluoro-5-(pent-1-en-1-yl)benzene | HCID 53632070 | — |
Reaction Steps
Phosphorus(v) oxide (64.5 g, 0.45 mol) is added to a stirred solution of compound 9A (35.0 g, 0.175 mol) in dry pentane (150 ml) at room temperature. The mixture is stirred at room temperature overnight (glc analysis revealed absence of starting material) and filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273680 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-82692c8c00af4fbca90d5793d6c3a70f |
| Source note | uspto-grants-1993_12 |