Thiophosgene → HCID 178505460, compound

HRID 327422Notes

Reaction equation

HRID 327422 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[OH:9].[C:10](Cl)(Cl)=[S:11]>O.C(OCC)C>[F:8][C:5]1[CH:6]=[CH:7][C:2]2[N:1]=[C:10]([SH:11])[O:9][C:3]=2[CH:4]=1

Participants

5

Reactant 2

HCID 10040ThiophosgeneHCID 1857632-Amino-5-fluorophenol

Product 1

HCID 178505460HCID 178505460, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3283Diethyl EtherSolvent

Procedure

2-Amino-5-fluorophenol [CAS:53981-24-1] (18.4 g) in 100 ml of water was stirred at room temperature while thiophosgene (16.8 g) was added dropwise as a solution in 100 ml of diethyl ether at such a rate that the resultant exotherm was controlled.

Sources & evidence

ORD record
ord-645dbbb60e834596b912c511d86f55e3
Source dataset
uspto-grants-1993_12
Patent number
US05273988

Reaction notes

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