HCID 19919303, compound → HCID 19919459, compound

HRID 327452Notes

Reaction equation

HRID 327452 reaction equation
C[O:2][C:3]1[CH:12]=[CH:11][C:10]2[N:13]=[CH:14][N:8]3[C:9]=2[C:4]=1[CH2:5][CH:6]([N:15]([CH2:19][CH2:20][CH3:21])[CH2:16][CH2:17][CH3:18])[CH2:7]3>Br>[CH2:19]([N:15]([CH2:16][CH2:17][CH3:18])[CH:6]1[CH2:5][C:4]2[C:3]([OH:2])=[CH:12][CH:11]=[C:10]3[N:13]=[CH:14][N:8]([C:9]=23)[CH2:7]1)[CH2:20][CH3:21]

Participants

3

Reactant 1

HCID 19919303HCID 19919303, compound

Product 1

HCID 19919459HCID 19919459, compound

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

5,6-Dihydro-7-methoxy-N,N-dipropyl-4H-imidazo(4,5,1-ij)quinolin-5-amine (1.0 g) was heated at 130° C. in 48% hydrobromic acid for 2 hours. The solution was cooled and was then evaporated under reduced pressure. The solid thus obtained was crystallized from methanol:ether; mp 270° C.

Workup

  1. temperatureThe solution was cooled
  2. customwas then evaporated under reduced pressure
  3. customThe solid thus obtained
  4. customwas crystallized from methanol

Sources & evidence

ORD record
ord-4b238e8197d14a089cb84c417f3359c5
Source dataset
uspto-grants-1993_12
Patent number
US05273975

Reaction notes

Loading…