Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 5-(Aminosulfonyl)-2-morpholin-4-ylbenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 2-Chloro-5-aminosulfonylbenzoic acid | HCID 66794 | — |
| 반응물 | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| 생성물 | 5-(Aminosulfonyl)-2-morpholin-4-ylbenzoic acid | HCID 4962116 | 85% |
반응 단계
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid (Example S) from 2-Chloro-5-sulfamoyl-benzoic acid (CAS: 97-04-1; Basu; D.-G.; J.Indian Chem.Soc.; 16; 1939; 100, 106) and morpholine and obtained in 85% yield. MS (m/e): 285.1 (MH− 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07427612B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-6fd99190e7aa42438846a375d1701087 |
| 출처 메모 | uspto-grants-2008_09 |