反应详情

600 ml of a solution of 18.3 g of 3,4,5-trimethoxyaniline in toluene was added to 140 ml of a solution of 48 ml of trichloromethyl chloroformate in toluene and the mixture was refluxed for 3 h. After cooling, the solvent was distilled off and the residue was distilled under reduced pressure (115° C./l mmHg) to obtain 15.53 g of 3,4,5-trimethoxyphenyl isocyanate.

1. temperaturethe mixture was refluxed for 3 h
2. temperatureAfter cooling
3. distillationthe solvent was distilled off
4. distillationthe residue was distilled under reduced pressure (115° C./l mmHg)