HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → [(2-Cyclobutyl-4-thiazolyl)methyl]triphenylphosphonium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 4-Chloromethyl-2-cyclobutyl-thiazole | HCID 18759094 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | [(2-Cyclobutyl-4-thiazolyl)methyl]triphenylphosphonium chloride | HCID 20084325 | 41.7% |
Reaction Steps
A mixture of 4.8 g of 4-chloromethyl-2-cyclobutyl-thiazole, 7.0 g of triphenylphosphine and 125 ml of toluene was heated to reflux for 16 hr and then cooled to room temperature. The mixture was then filtered to yield 4.8 g of [(2-cyclobutyl-4-thiazolyl)methyl]triphenylphosphonium chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273986 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-73cd87565a8d4de0b4d3f8e685eaf428 |
| Source note | uspto-grants-1993_12 |