4-Iodophenol → HCID 44459431, compound

HRID 327738Notes

Reaction equation

HRID 327738 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[S:10]([N:13]=C=O)(=[O:12])=[O:11]>C1(C)C=CC=CC=1>[I:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][S:10](=[O:12])(=[O:11])[NH2:13])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 108944-IodophenolHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 44459431HCID 44459431, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This compound was prepared according to the procedure of Example 56. A mixture of 22.0 g (0.1 mole) of 4-iodophenol (Aldrich) and 9.1 ml (14.8 g, 0.105 mole) of chlorosulfonyl isocyanate in 100 ml of toluene gave 23.8 g (80%) of the title compound as a white solid, mp 146°-147° C.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-19fc9c8b947a439181b2baabe573d95c
Source dataset
uspto-grants-1993_12
Patent number
US05273993

Reaction notes

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