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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327760Generated: October 30, 2026

1-Chloro-4-(chloromethyl)benzene → 1-(p-Chlorobenzyl)-1-[4-(quinolin-2-ylmethoxy)phenyl]hydrazine

https://huagongshe.com/reaction/327760

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-(chloromethyl)benzeneHCID 7723—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-(Quinolin-2-ylmethoxy)phenylhydrazineHCID 15225068—
CatalystTetrabutylammonium BromideHCID 74236—
Product1-(p-Chlorobenzyl)-1-[4-(quinolin-2-ylmethoxy)phenyl]hydrazineHCID 9908402—

Reaction Steps

reacting the 4-(quinolin-2-ylmethoxy)phenylhydrazine product of step (4) with p-chlorobenzyl chloride, tetrabutylammonium bromide and diisopropylethylamine to yield 1-(p-chlorobenzyl)-1-[4-(quinolin-2-ylmethoxy)phenyl]hydrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05274096
Source datasetuspto-grants-1993_12
ORD IDord-101dfec2cd4143ee99ca5b6374c7cd9f
Source noteuspto-grants-1993_12