反应详情

4-Mesyloxybenzocyclobutene is prepared by reaction between 4-hydroxybenzocyclobutene and mesyl chloride (methanesulfonyl chloride) in pyridine, using excess pyridine as solvent. The mesyloxy compound is reacted with maleimide, otherwise as in paragraph (a), to produce 4-(N-maleimidyl)benzocyclobutene, which is hydrolyzed with hydrazine hydrate to 4-aminobenzocyclobutene, otherwise as in paragraph (b).