Succinic Acid → HCID 131716353, compound

Participants

Reaction Steps

The diamine of Example 40 (274 mg) in methanol (3 ml) is treated with succinic acid (283 mg) in methanol (3 ml). The reaction is stirred at 20°-25° for 18 hours. A white precipitate forms which is collected by filtration. This is then recrystallized from methanol-diethyl ether to give a solid, mp 164°-166° C. Second crop mp 164°-165° C. (PLA2)

Provenance & Evidence