HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 9-bromononanoate → (E)-9-[3-(6-Hydroxy-1-hexynyl)-2-(3-methoxy-3-oxo-1-propenyl)phenoxy]nonanoic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 9-bromononanoate | HCID 554142 | — |
| Reactant | (E)-3-[2-Hydroxy-6-(6-hydroxy-1-hexynyl)phenyl]-2-propenoic Acid Methyl Ester | HCID 67780365 | — |
| Product | (E)-9-[3-(6-Hydroxy-1-hexynyl)-2-(3-methoxy-3-oxo-1-propenyl)phenoxy]nonanoic Acid Methyl Ester | HCID 67780053 | 71% |
Reaction Steps
Using the procedure of example 122, (E)-3-[2-hydroxy-6-(6-hydroxy-1-hexynyl)phenyl]-2-propenoic acid methyl ester (example 176) was alkylated with methyl 9-bromononanoate giving the title compound, in 71% yield, as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273999 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-814f389ddb484e6f8281e2277c0c2323 |
| Source note | uspto-grants-1993_12 |