HCID 53952491, compound → HCID 19921959, compound

HRID 328041Notes

Reaction equation

HRID 328041 reaction equation
C([O:3][C:4](=[O:45])[CH2:5][CH2:6][C:7]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH2:18][C:19]([O:21]CC)=[O:20])=[CH:14][CH:15]=2)[CH:10]=[CH:9][C:8]=1[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]1[CH:41]=[CH:40][C:34]2[C:35](=[O:39])[CH2:36][CH2:37][O:38][C:33]=2[C:32]=1[CH2:42][CH2:43][CH3:44])C>CCCCCC.C(OCC)(=O)C>[C:19]([CH2:18][O:17][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][CH:14]=1)[C:7]([CH2:6][CH2:5][C:4]([OH:45])=[O:3])=[C:8]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]1[CH:41]=[CH:40][C:34]3[C:35](=[O:39])[CH2:36][CH2:37][O:38][C:33]=3[C:32]=1[CH2:42][CH2:43][CH3:44])[CH:9]=[CH:10]2)([OH:21])=[O:20]

Participants

3

Reactant 1

HCID 53952491HCID 53952491, compound

Product 1

HCID 19921959HCID 19921959, compoundYield 52.6%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Starting with 0.736 g (1.19 mmol) of 2-[[5-[(3,4-dihydro-4-oxo-8-propyl-2H-1-benzopyran-7-yl)oxy]pentyl]oxy]-6-(2-ethoxy-2oxoethoxy)-1-naphthalenepropanoic acid ethyl ester from the preceding example, the title compound (0.352 g; 52.6%) was obtained as a white solid, mp 160.5°-163° C. (recrystallized from hexane-ethyl acetate), using the procedure of example 226.

Sources & evidence

ORD record
ord-d34c5424bb354c1582170b3e2c980699
Source dataset
uspto-grants-1993_12
Patent number
US05273999

Reaction notes

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