Benzoyl chloride → HCID 22751148, compound

Participants

Reaction Steps

1.48 Grams of 3-hydrazino-4-methyl-6-morpholinopyridazine and 1.8 grams of triethylamine are dissolved in 200 milliliters of dioxane. 3.5 Grams benzoyl chloride are added to the resulting mixture, and the mixture is heated at the boiling temperature under reflux for 3 hours. The mixture is evaporated to dryness, and the 8-methyl-6- -morpholino-3-phenyl-s-triazolo[4,3-b]pyridazine product is obtained as a residue. The product is washed with water, recrystallized from ethanol and found to melt at a temperature of 271°-273° C. 3.6 Grams of the product are obtained.

Provenance & Evidence