Hydrochloric Acid → HCID 86734607, compound

HRID 328079Notes

Reaction equation

[ClH:1].C(OC([NH:12][C@H:13]([C:29]([NH:31][O:32][P:33]([CH3:36])(=[O:35])[OH:34])=[O:30])[CH2:14][CH2:15][CH2:16][CH2:17][NH:18]C(OCC1C=CC=CC=1)=O)=O)C1C=CC=CC=1>>[ClH:1].[ClH:1].[NH2:12][C@H:13]([C:29]([NH:31][O:32][P:33]([CH3:36])(=[O:34])[OH:35])=[O:30])[CH2:14][CH2:15][CH2:16][CH2:17][NH2:18]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 86734609HCID 86734609, compound

Product 1

HCID 86734607HCID 86734607, compound

Procedure

In a manner analogous to Example 1 b), but with hydrogenation in the presence of 2-N hydrochloric acid, starting from [[N2,N6 -bis(benzyloxycarbonyl)-L-lysyl]amino]-methylphosphonic acid there was obtained (L-lysylamino)-methylphosphonic acid dihydrochloride of melting point 212°-217° C (decomposition); [α]D20 = +22.35° (c = 1% in water).

Sources & evidence

ORD record: ord-7b188153c5ca4fdead724569f9d2fef0
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04016148

Reaction notes

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