Thionyl Chloride → HCID 86734598, compound

HRID 328112Notes

Reaction equation

HRID 328112 reaction equation
[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][C:13]([OH:15])=O)=[CH:8][CH:7]=2)[CH2:5][CH2:4][N:3]=[CH:2]1.S(Cl)([Cl:18])=O>C1C=CC=CC=1>[ClH:18].[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][C:13]([Cl:18])=[O:15])=[CH:8][CH:7]=2)[CH2:5][CH2:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68117104HCID 68117104, compound

Product 1

HCID 86734598HCID 86734598, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

10 g of 4-(2-imidazolinyl)-phenylacetic acid (melting point 196° to 197° C) were stirred with 150 ml of anhydrous benzene and 90 ml of thionyl chloride for 5 hours at 50° to 60° C. After cooling, the crystalline product was filtered off with suction, washed with anhydrous benzene and dried under reduced pressure. 11 g of 4-(2-imidazolinyl)-phenyl-acetyl chloride-hydrochloride were obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationthe crystalline product was filtered off with suction
  3. washwashed with anhydrous benzene
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-7bb00787c4f744c3ae1a8d6e0c536b09
Source dataset
uspto-grants-1977_04
Patent number
US04016159

Reaction notes

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