Hydrochloric Acid → HCID 21444156, compound

Participants

Reaction Steps

In a mixed solution of 0.5g of sodium hydroxide, 5 ml of water and 2ml of metanol 0.7g of methyl 3-nitro-4-propargyloxyphenylacetate was added and heated on a water bath for 30 minutes. After cooling, the solution was neutralized with 10% hydrochloric acid and the thus obtained crystals were recrystallized from ether-n-hexane to give the object compound having m.p. 135° - 137° C in a yield of 0.6g (90.6%).

Provenance & Evidence