Acrylonitrile → 3-[(3-Hydroxypropyl)amino]propanenitrile

HRID 328182Notes

Reaction equation

HRID 328182 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][OH:5].[C:6](#[N:9])[CH:7]=[CH2:8]>>[C:6]([CH2:7][CH2:8][NH:1][CH2:2][CH2:3][CH2:4][OH:5])#[N:9]

Participants

3

Reactant 2

HCID 7855AcrylonitrileHCID 90863-Amino-1-propanol

Product 1

HCID 135569403-[(3-Hydroxypropyl)amino]propanenitrile

Procedure

A solution of 75 g. (1 mole) of 3-aminopropanol is stirred while 54 g. (1 mole) of acrylonitrile is added dropwise. After being allowed to stand at room temperature for several hours and preferably overnight, the reaction mixture is concentrated under reduced pressure at 50° yielding 3-(2-cyanoethyl)aminopropanol.

Workup

  1. concentrationthe reaction mixture is concentrated under reduced pressure at 50°

Sources & evidence

ORD record
ord-ec213696efae4142b407e4af2116f5ac
Source dataset
uspto-grants-1977_04
Patent number
US04016209

Reaction notes

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