HCID 21441246, compound → HCID 21441250, compound

HRID 328299Notes

Reaction equation

HRID 328299 reaction equation
[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][C:17]([CH3:20])=[C:11]([C:12]([O:14]CC)=[O:13])[C:10]=1[C:21]([O:23]CC)=[O:22])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O.C(O)C>[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][C:17]([CH3:20])=[C:11]([C:12]([OH:14])=[O:13])[C:10]=1[C:21]([OH:23])=[O:22])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 21441246HCID 21441246, compound

Product 1

HCID 21441250HCID 21441250, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent2×

Procedure

The crude ester is heated under reflux for 3 hours in 150 ml water and 100 ml 95% ethanol containing 20 g NaOH. The mixture is poured into water and the resulting solid removed by filtration, washed with water and air-dried to give 24.4 g crude 3-benzyloxy-6-methylphthalic acid.

Workup

  1. customthe resulting solid removed by filtration
  2. washwashed with water
  3. customair-dried

Sources & evidence

ORD record
ord-b0782eb45d984b0ca30835b37108f45e
Source dataset
uspto-grants-1977_04
Patent number
US04017299

Reaction notes

Loading…