Water → HCID 178443253, compound

Participants

Reaction Steps

A solution of 1.22 g. (3.0 mmoles) of 1-(5-carboxypentyloxycarbonyl)-2-(4-thiazolyl)-benzimidazole potassium salt in 10 ml. of water is added gradually to a stirred solution of 3.3 mmoles of n-dodecylguanidine hydrochloride in 20 ml. of water containing isopropanol. The product precipitates immediately and is stirred for 45 minutes, filtered and washed with water, methanol and acetone affording 1.19 g. of 1-(5-carboxypentyloxycarbonyl)-2-(4-thiazolyl)-benzimidazole n-dodecylguanidinium salt,

Provenance & Evidence