HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 7-Chloro-2-[[1-(methoxycarbonyl)ethylidene]-hydrazino]-5-phenyl-3H-1,4-benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 7-chloro-2-[(1-carboxyethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine | HCID 54054180 | — |
| Product | 7-Chloro-2-[[1-(methoxycarbonyl)ethylidene]-hydrazino]-5-phenyl-3H-1,4-benzodiazepine | HCID 53729966 | — |
Reaction Steps
To this solution of 7-chloro-2-[(1-carboxyethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine under nitrogen, is added with stirring, 50 ml. (0.015 mole) of an ethereal 0.3 molar solution of diazomethane. After 10 minutes the solution is evaporated giving 7-chloro-2-[[1-(methoxycarbonyl)ethylidene]-hydrazino]-5-phenyl-3H-1,4-benzodiazepine is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017492 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-173bfe818a744600856ff45cfda7f2e2 |
| Source note | uspto-grants-1977_04 |