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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 328412Generated: October 31, 2026

2-Oxo-5-piperidinopentanoic acid → 7-nitro-2-[(1-carboxy-4-piperidinobutylidene)-hydrazino]-5-phenyl-3H-1,4-benzodiazepine

https://huagongshe.com/reaction/328412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxo-5-piperidinopentanoic acidHCID 21441681—
ReactantHCID 22768399HCID 22768399—
Product7-nitro-2-[(1-carboxy-4-piperidinobutylidene)-hydrazino]-5-phenyl-3H-1,4-benzodiazepineHCID 54309535—

Reaction Steps

In the manner given in Example 13, 7-nitro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine can be stirred with 2-oxo-5-piperidinopentanoic acid at room temperature to give 7-nitro-2-[(1-carboxy-4-piperidinobutylidene)-hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04017492
Source datasetuspto-grants-1977_04
ORD IDord-a0fe5fd48b1d458b993b243af9db277d
Source noteuspto-grants-1977_04