HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-hydrazino-5-phenyl-3H-1,4-benzodiazepine → 2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-hydrazino-5-phenyl-3H-1,4-benzodiazepine | HCID 12612389 | — |
| Reactant | 4-(Dimethylamino)-2-oxobutanoic acid | HCID 21441574 | — |
| Product | 2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine | HCID 53980318 | — |
Reaction Steps
In the manner given in Example 13, 2-hydrazino-5-phenyl-3H-1,4-benzodiazepine can be stirred with 4-(dimethylamino)-2-oxobutyric acid at room temperature to give 2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017492 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-3e74a5f4b9e94886b87e8bfc5e91b106 |
| Source note | uspto-grants-1977_04 |