Ammonia → HCID 21442303, compound

HRID 328466Notes

Reaction equation

HRID 328466 reaction equation
[CH3:1][N:2]([CH3:8])[C:3]([N:5]=[C:6]=[S:7])=[O:4].[NH3:9]>C(Cl)Cl>[CH3:1][N:2]([CH3:8])[C:3]([NH:5][C:6]([NH2:9])=[S:7])=[O:4]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 12273101HCID 12273101, compound

Product 1

HCID 21442303HCID 21442303, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
0 °C

Procedure

To a solution of 65 parts of dimethylcarbamoylisothiocyanate (a compound of formula VI) in 350 parts methylene chloride are added within 10 minutes at 0° C, 50 parts of conc. aqueous ammonia with good agitation. The resulting slurry of crystals is stirred for an additional 15 minutes at 0° C and then filtered to give 70 parts of 1,1-dimethyl-4-thiobiuret (a compound of formula VII), m.p. 184°-185° C.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-65fc0e58174a49e08ef6ea276d17462d
Source dataset
uspto-grants-1977_04
Patent number
US04017529

Reaction notes

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