Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 12273101 | HCID 12273101 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21442303 | HCID 21442303 | — |
Reaction Steps
To a solution of 65 parts of dimethylcarbamoylisothiocyanate (a compound of formula VI) in 350 parts methylene chloride are added within 10 minutes at 0° C, 50 parts of conc. aqueous ammonia with good agitation. The resulting slurry of crystals is stirred for an additional 15 minutes at 0° C and then filtered to give 70 parts of 1,1-dimethyl-4-thiobiuret (a compound of formula VII), m.p. 184°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04017529 |
|---|
| Source dataset | uspto-grants-1977_04 |
|---|
| ORD ID | ord-65fc0e58174a49e08ef6ea276d17462d |
|---|
| Source note | uspto-grants-1977_04 |
|---|
