Water → HCID 152774376, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 58.5 parts of 1,1-dimethyl-4-thiobiuret in 200 parts of water, 200 parts of methanol and 32 parts of 50% aqueous sodium hydroxide are added at 25° C. within 10 minutes 62.5 parts of iodoethane. The reaction mass is then stirred at 25° C. for 2 hours. Evaporation of the methanol and part of the water under vacuum gives 64 parts of crude ethyl 4,4-dimethylthioallophanimidate (a compound of formula II), which is recrystallized from water-methanol (50:50) and shows a melting point of 90°-93° C.

Provenance & Evidence