HuagongsheHuagongshe Chemistry Print Report · For research reference only
Uridine → Tetrahydrouridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Uridine | HCID 6029 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Water | HCID 962 | — |
| Product | Tetrahydrouridine | HCID 29243 | — |
| Product | HCID 22796909 | HCID 22796909 | — |
Reaction Steps
In the manner given in Example 2B, uridine was directly reduced with a rhodium on alumina catalyst in a solvent medium consisting of 1 part concentrated ammonium hydroxide and 99 parts water to give 4-hydroxy-1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone and 1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017606 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-0dcbfe606de640439ca678b1b5369842 |
| Source note | uspto-grants-1977_04 |