Water → HCID 21442792, compound

Participants

Reaction Steps

To a suspension of lithium aluminium hydride (0.08 g) in tetrahydrofuran was added a solution of 5-(4-acetyl-2-morpholinylmethyl)-10,11-dihydro-5H-dibenz[b,f]azepine (0.34 g) in tetrahydrofuran under ice-cooling, and the resulting mixture was stirred under reflux for 1 hour. the reaction mixture was cooled, admixed with water and extracted with benzene. The benzene extract was washed with water, dried over anhydrous sodium sulfate and evaporated to afford 5-(4-ethyl-2-morpholinylmethyl)-10,11-dihydro-5H-dibenz[b,f]azepine as an oily substance. M.P. 210°-211° C (oxalate).

Provenance & Evidence