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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32864Generated: October 25, 2026

Hydrochloric Acid → 2-Amino-3,3-diphenylpropanoic acid hydrochloride

https://huagongshe.com/reaction/32864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPhenylalanine,N-acetyl--phenyl-HCID 11022400—
Product2-Amino-3,3-diphenylpropanoic acid hydrochlorideHCID 19772460—

Reaction Steps

A solution (21 mL) of 2-acetylamino-3,3-diphenylpropanoic acid (2.83 g, 10 mmol) in concentrated hydrochloric acid was stirred at 90° C. for 5 hrs, and the reaction mixture was cooled in an ice bath to allow solid precipitation. The solid was collected by filtration and dried to give the title compound (2.65 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427688B2
Source datasetuspto-grants-2008_09
ORD IDord-180659972f66413a9d3b5f339b90f27f
Source noteuspto-grants-2008_09