Sodium Methoxide → 4-Methoxy[1]benzothieno[3,2-d][1,2,3]triazine

HRID 328674Notes

Reaction equation

HRID 328674 reaction equation
Cl[C:2]1[C:3]2[S:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[C:4]=2[N:5]=[N:6][N:7]=1.[CH3:15][O-:16].[Na+]>CO>[CH3:15][O:16][C:2]1[C:3]2[S:10][C:9]3[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=3[C:4]=2[N:5]=[N:6][N:7]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 12269873HCID 12269873, compound

Product 1

HCID 3234304-Methoxy[1]benzothieno[3,2-d][1,2,3]triazine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A 2.2 g. portion of the product of Example 1 was stirred at reflux temperature in 100 ml. of methanol with 0.7 g. of sodium methoxide for one hour. When the reaction mixture was cooled, the product, 1.9 g. of 4-methoxy[1]-benzothieno[3,2-d]-v-triazine, m.p. 165°-167° C., crystallized and needed no further purification.

Workup

  1. temperatureat reflux temperature in 100 ml
  2. temperatureWhen the reaction mixture was cooled
  3. customof 4-methoxy[1]-benzothieno[3,2-d]-v-triazine, m.p. 165°-167° C., crystallized
  4. customno further purification

Sources & evidence

ORD record
ord-41716bf0ef4347d887d34487b671ca35
Source dataset
uspto-grants-1977_04
Patent number
US04018768

Reaction notes

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