Hydrochloric Acid → HCID 12830409, compound

HRID 328684Notes

Reaction equation

HRID 328684 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([OH:21])[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3=[N:18][CH2:19][CH2:20][N:10]23)=[CH:5][CH:4]=1>CCOCC>[Cl:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]([C:17]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[C:11]2[NH:18][CH2:19][CH2:20][N:10]=2)=[O:21])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 4020Mazindol

Product 1

HCID 12830409HCID 12830409, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The hydrochloride was prepared by adding a solution of hydrogen chloride in ether to a suspension of 5-(4-chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]isoindole. After stirring for 30 minutes a crystalline crop was collected and recrystallized from a mixture of chloroform and ether to give white prisms melting at 168°-171° dec. Ultraviolet inflexion (2-propanol) at 220 μ (ε = 22,000), maxima at 252 μ (ε = 12,900), 266 μ (ε = 13,000); infrared absorption (KBr) at 1670 cm-1.

Workup

  1. customwas collected
  2. customrecrystallized from a mixture of chloroform and ether

Sources & evidence

ORD record
ord-5017a882b0494abeb5b9072a4b24769f
Source dataset
uspto-grants-1977_04
Patent number
US04018765

Reaction notes

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