Hydrochloric Acid → HCID 21439769, compound

HRID 328687Notes

Reaction equation

HRID 328687 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[NH:13][CH2:14][CH2:15][N:16]=1)=[O:5].Cl.CO>CCOCC>[ClH:1].[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[NH:16][CH2:15][CH2:14][N:13]=1)=[O:5]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 21439770HCID 21439770, compound

Product 1

HCID 21439769HCID 21439769, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a hot solution of 6.0 g. (21.2 moles) of 2-[2-(2-chlorobenzoyl)phenyl]-2-imidazoline in 25 ml. of 6 N methanolic hydrogen chloride and 35 ml. of methanol was added 200 ml. of ether and the solution cooled. Filtration gave 2-[2-(2-chlorobenzoyl)-phenyl]-2-imidazoline hydrochloride, m.p. 178°-180° dec. Dilution of the mother liquors with 200 ml. of ether followed by cooling and filtering afforded an additional quantity of hydrochloride. Recrystallization from methanol-ether gave colorless prisms, m.p. 178°-180° dec.

Workup

  1. filtrationFiltration

Sources & evidence

ORD record
ord-54d0c8173d4f4f5bb6adcef277fb00dd
Source dataset
uspto-grants-1977_04
Patent number
US04018765

Reaction notes

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