Hydrochloric Acid → 2-Amino-3,3-bis(4-fluorophenyl)propanoic acid hydrochloride

Beteiligte Stoffe

Reaktionsschritte

A solution (144 mL) of 2-acetylamino-3,3-bis(4-fluorophenyl)propanoic acid (25.34 g, 79.9 mmol) in concentrated hydrochloric acid was stirred at 90° C. for 5 hrs, and cooled in an ice bath to allow solid precipitation. The solid was collected by filtration and dried to give the title compound (22.79 g).

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