HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 70619885, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | O-Xylene | HCID 7237 | — |
| Reactant | 1a,2,7,7a-Tetrahydro-3,6-dimethoxynaphth[2,3-b]oxirene | HCID 12367003 | — |
| Reactant | 2-(2-Methylphenyl)piperazine | HCID 55253315 | — |
| Product | HCID 70619885 | HCID 70619885 | — |
Reaction Steps
A solution of 10.3 g of 2,3-epoxy-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene, 8.8 g of o-tolylpiperazine, and 2 ml of absolute ethanol in 100 ml of xylene is refluxed for 4 days. The reaction mixture is cooled to room temperature, and the resulting crystalline solid filtered off and washed with ether to give 15.2 g of crude product. Recrystallization from ethanol/methanol gives 4 g of the title compound, melting point 217°-219° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04018773 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-18d42665ab5f470fb02405dbbe17a320 |
| Source note | uspto-grants-1977_04 |