Ammonium Hydroxide → HCID 21439879, compound

HRID 328715Notes

Reaction equation

HRID 328715 reaction equation
Br[C:2]1[CH:15]=[CH:14][C:5]2[S:6](=[O:13])[C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[OH-].[NH4+:17]>>[NH2:17][C:2]1[CH:15]=[CH:14][C:5]2[S:6](=[O:13])[C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 15959584HCID 15959584, compound

Product 1

HCID 21439879HCID 21439879, compound

Procedure

A mixture of 150 g. of crude 2-bromodibenzothiophene-5-oxide, 160 g. of cuprous bromide and 1700 ml. of ammonium hydroxide is heated at 200° C. in a pressure reactor for about 12 hours. The mixture is then filtered, and the residue is washed with water, then heated in methanol and filtered hot. The product is recrystallized by cooling and separated by filtration to give 2-aminodibenzothiophene-5-oxide, m.p. 169°-172° C.

Workup

  1. additionA mixture of 150 g
  2. filtrationThe mixture is then filtered
  3. washthe residue is washed with water
  4. temperatureheated in methanol
  5. filtrationfiltered hot
  6. customThe product is recrystallized
  7. temperatureby cooling
  8. customseparated by filtration

Sources & evidence

ORD record
ord-b92df0d28a6c43b2a3f2f41236386579
Source dataset
uspto-grants-1977_04
Patent number
US04018780

Reaction notes

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