Methyl iodide → HCID 21440002, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of ethyl 2-(2-anilinothiazol-4-yl)-propionate (6.15 g), methyl iodide (17 ml) and ethanol (17 ml) is heated at 100° C for 11.5 hours in a sealed tube. The resultant mixture is treated with potassium carbonate in the same manner as in Example 1 (2) to give ethyl 2-(2-phenylimino-3-methyl-4-thiazolin-4-yl)propionate (1.6 g) melting at 80°-81° C (recrystallized from ether/hexane).

Provenance & Evidence