p-Toluenesulfonic acid monohydrate → HCID 21317594, compound

HRID 328761Notes

Reaction equation

HRID 328761 reaction equation
[C:1]([O:4][CH:5]([CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[CH2:6][CH2:7][CH2:8][C:9]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])(C(OC(C)(C)C)=O)[C:10]([O:12]C(C)(C)C)=[O:11])(=[O:3])[CH3:2].O.C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[C:10]([CH:9]([CH2:8][CH2:7][CH2:6][CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])([OH:12])=[O:11]

Participants

4

Reactant 2

HCID 521998p-Toluenesulfonic acid monohydrateHCID 21317623Di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)-malonate

Product 1

HCID 21317594HCID 21317594, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)malonate (104.12 g., 0.187 mole), p-toluenesulfonic acid monohydrate (3.30 g.) and toluene (330 ml.) is heated under reflux for 91/2 hours.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 91/2 hours

Sources & evidence

ORD record
ord-aeb816daa3b3446483b00171bf3a8e0d
Source dataset
uspto-grants-1977_04
Patent number
US04018802

Reaction notes

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