Thionyl Chloride → HCID 88821752, compound

HRID 329024Notes

Reaction equation

HRID 329024 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][CH:14]=1)[O:7][CH2:8][C:9](O)=[O:10])(=[NH:3])[NH2:2].S(Cl)([Cl:17])=O>>[ClH:17].[C:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][CH:14]=1)[O:7][CH2:8][C:9]([Cl:17])=[O:10])(=[NH:3])[NH2:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 12222283HCID 12222283, compound

Product 1

HCID 88821752HCID 88821752, compound

Procedure

19.4 g of 3-amidinophenoxyacetic acid were heated under reflux, while well stirring, for 2 hours with 70 ml of thionyl chloride. After cooling, filtration with suction and washing with anhydrous diethyl ether, 21 g of 3-amidinophenoxyacetic acid chloride hydrochloride were obtained; decomposition point 149° to 151° C.

Workup

  1. temperatureunder reflux
  2. temperatureAfter cooling
  3. filtrationfiltration with suction
  4. washwashing with anhydrous diethyl ether

Sources & evidence

ORD record
ord-16d9569b6f38433aa82e185d50c4b9db
Source dataset
uspto-grants-1977_04
Patent number
US04018933

Reaction notes

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