反应详情

A solution of 37 g of 2-(1-benzyl-4-ethyl-4-piperidyloxy)-ethanol in 300 ml of absolute ethanol was reacted with hydrogen at 50° C in the presence of 4 g of 10% palladized charcoal until the theoretical amount of hydrogen was absorbed (about 3 hours) and the catalyst was filtered off. The ethanol was evaporated off and the residue was distilled to obtain 19.2 g of 2-(4-ethyl-4-piperidyloxy)-ethanol as a colorless oil boiling at 102°-106° C at 0.5 mm Hg.

1. customwas absorbed (about 3 hours)
2. filtrationthe catalyst was filtered off
3. customThe ethanol was evaporated off
4. distillationthe residue was distilled