Acetic Acid → HCID 178519227, compound

HRID 329217Notes

Reaction equation

HRID 329217 reaction equation
[CH:1]1([S:7][CH2:8][CH2:9][N+:10]2[N-:11][O:12][C:13](=[O:15])[CH:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C([O-])(=O)C.[K+].C(O)(=O)C.[Br:25]Br>O>[CH:1]1([S:7][CH2:8][CH2:9][N+:10]2[N-:11][O:12][C:13](=[O:15])[C:14]=2[Br:25])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

6

Reactant 4

HCID 176Acetic Acid2×HCID 24408BromineHCID 517044Potassium AcetateHCID 178516776HCID 178516776, compound

Product 1

HCID 178519227HCID 178519227, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4 Parts of 3-[2-(cyclohexylthio)ethyl]sydnone is stirred with 4 parts of potassium acetate in 40 parts by volume of acetic acid while 2.8 parts of bromine in 10 parts by volume of acetic acid is added dropwise. Stirring is continued for 30 minutes and then the reaction mixture is poured into water, filtered and washed with water to give 3-[2-(cyclohexylthio)ethyl]-4-bromosydnone.

Workup

  1. additionis added dropwise
  2. filtrationfiltered
  3. washwashed with water

Sources & evidence

ORD record
ord-3180196711fe42aeb0b7315040085237
Source dataset
uspto-grants-1977_04
Patent number
US04020079

Reaction notes

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