HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-Ethylsulfanyl-1-(5-nitro6-trifluoromethyl-1H-indol-2-yl)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-ethylsulfanyl-1-(1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indol-2-yl)-ethanol | HCID 11502477 | — |
| Product | 2-Ethylsulfanyl-1-(5-nitro6-trifluoromethyl-1H-indol-2-yl)-ethanol | HCID 11681533 | — |
Reaction Steps
This compound was prepared using the general de-protection procedure described in General Procedures Example B, starting from 2-ethylsulfanyl-1-(1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indol-2-yl)-ethanol (1.52 g, 3.69 mmol) and 4M sodium hydroxide as base (1.8 mL, 7.38 mmol) to yield the title compound as a bright yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427682B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-38b43f83509a41fe8be53869d03cf5d2 |
| Source note | uspto-grants-2008_09 |