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HRID329360

反应详情

EQUATION

反应方程式

HRID 329360 的结构方程式

REACTANTS

反应物

4
结构：c1ccncc1
HCID1049

Pyridine

C5H5N

结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2OC1CC1
HCID14882764

未命名化合物

结构：CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H](OC5CC5)[C@@]4(C)CC[C@@H]32)C1
HCID67896754

未命名化合物

PRODUCTS

生成物

2
结构：C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](OC(=O)CCC5CCCC5)CC[C@@]43C)[C@@H]1CC[C@@H]2OC1CC1
HCID67896728

未命名化合物

结构：C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](OC(=O)CCc5ccccc5)CC[C@@]43C)[C@@H]1CC[C@@H]2OC1CC1
HCID67896733

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

17β-(Cyclopropyloxy)androst-5-en-3β-ol is treated with acetic anhydride and pyridine. The mixture is poured into water and extracted with ethyl acetate. The ethyl acetate layer is separated and dried and the solvent is evaporated to leave as a residue, 3β-acetyloxy-17β-(cyclopropyloxy)androst-5-ene. 3β-(Cyclopentanepropionyloxy)-17β-(cyclopropyloxy)androst-5-ene and 3β-(benzenepropionyloxy)-17β-(cyclopropyloxy)androst-5-ene are obtained in a similar way using the appropriate acid chlorides.

WORKUP

后处理

  1. extractionextracted with ethyl acetate
  2. customThe ethyl acetate layer is separated
  3. customdried
  4. customthe solvent is evaporated
  5. customto leave as a residue