HRID329369

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79266

4-Nitrophenethyl bromide

C8H8BrNO2

HCID11310042

7-NITRO-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE

C10H12N2O2

PRODUCTS

生成物

结构：O.O=[N+]([O-])c1ccc(CCN2CCc3ccc([N+](=O)[O-])cc3CC2)cc1.O=[N+]([O-])c1ccc(CCN2CCc3ccc([N+](=O)[O-])cc3CC2)cc1

HCID88599941

未命名化合物

PROCEDURE

实验过程

The title compound was prepared similarly to Preparation 2 by the reaction of 7-nitro-1,2,4,5-tetrahydro-3H-3-benzazepine (0.5 g) and 4-nitrophenethyl bromide (0.6 g), which, after 18 hours reflux, gave the title compound as an oil, yield 0.29 g.

WORKUP

后处理

temperaturereflux

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2b708feff62a4e0a8d1dae268f1ea493
来源数据集: uspto-grants-1990_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04891372
来源说明: uspto-grants-1990_01

反应 SMILES

[N+:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH2:12][C:6]=2[CH:5]=1)([O-:3])=[O:2].[N+:15]([C:18]1[CH:26]=[CH:25][C:21]([CH2:22][CH2:23]Br)=[CH:20][CH:19]=1)([O-:17])=[O:16]>>[OH2:2].[N+:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][CH2:9][N:10]([CH2:23][CH2:22][C:21]3[CH:20]=[CH:19][C:18]([N+:15]([O-:17])=[O:16])=[CH:26][CH:25]=3)[CH2:11][CH2:12][C:6]=2[CH:5]=1)([O-:3])=[O:2].[N+:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][CH2:9][N:10]([CH2:23][CH2:22][C:21]3[CH:20]=[CH:19][C:18]([N+:15]([O-:17])=[O:16])=[CH:26][CH:25]=3)[CH2:11][CH2:12][C:6]=2[CH:5]=1)([O-:3])=[O:2]