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HRID329553

反应详情

EQUATION

反应方程式

HRID 329553 的结构方程式

REACTANTS

反应物

3
结构：O=C(CCCN[C@@H](CS)C(=O)O)OCC1c2ccccc2-c2ccccc21
HCID54540940

未命名化合物

结构：O=CCCN[C@H](C(=O)O)C(CS)OCC1c2ccccc2-c2ccccc21
HCID131716236

未命名化合物

结构：Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](Cc2ccc(OCc3ccccc3)cc2)C(=O)OCc2ccccc2)cc1
HCID178427519

未命名化合物

PRODUCTS

生成物

4
结构：NCC(=O)O
HCID750

Glycine

C2H5NO2

结构：N[C@@H](Cc1ccc(O)cc1)C(=O)O
HCID6057

L-Tyrosine

C9H11NO3

结构：N[C@@H](Cc1ccccc1)C(=O)O
HCID6140

L-Phenylalanine

C9H11NO2

结构：CC[C@H](C)[C@H](N)C(=O)O
HCID6306

DL-Isoleucine

C6H13NO2

PROCEDURE

实验过程

By following the procedure of Examples 5 to 12, but replacing N-(t-butyloxycarbonyl)-S-(4-(9-fluorenylmethoxy)-4-oxobutyl-L-cysteine with N-(t-butyloxycarbonyl)-S-(3-(9-fluorenylmethoxy)-3-oxopropyl-L-homocysteine, and replacing H-Asn-Ser(Bzl)-Phe-Arg(Tos)-Tyr(Bzl)-OCH3 with H-Asn-Ser(Bzl)-Phe-Arg(Tos)-Tyr(Bzl)-OBzl, rat[(CH2CH2CO)105, hCys121 ]ANF-(105-126) is obtained Amino acid analysis of the product (1,Q=CH2CH2, R1=Phe, R2 =Gly, R3 =Ile, R4 =Phe, R5 =Tyr, X=S, Y1 des-Y and W is hydroxy) gave Asn+Asp (2.00), Ser (1.78), Gln (1.01), Gly(5.18), Ala (1.00), Ile (1.80), Leu (1.02), Tyr (0.99), Phe (2.00), Arg (3.45). Molecular weight was determined by FAB mass spectroscopy: C102H156N32O30S requires 2342.6: found, 2342M+.