N-Methylhydrazinecarbothioamide → HCID 14348270, compound

HRID 329572Notes

Reaction equation

HRID 329572 reaction equation
[CH2:1]([S:8][C:9](SCC1C=CC=CC=1)=[C:10]([C:15]#[N:16])[C:11]([O:13][CH3:14])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:25][NH:26][C:27](=[S:30])[NH:28][NH2:29]>C(O)C>[NH2:16][C:15]1[N:28]([C:27](=[S:30])[NH:26][CH3:25])[N:29]=[C:9]([S:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:10]=1[C:11]([O:13][CH3:14])=[O:12]

Participants

4

Reactant 2

HCID 2723853N-MethylhydrazinecarbothioamideHCID 2755381HCID 2755381, compound

Product 1

HCID 14348270HCID 14348270, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

45.11 g (0.127 mol) Methyl 3,3-dibenzylthio-2-cyanoacrylate and 13.35 g (0.127 mol) 4-methylthiosemicarbazide in 225 ml ethanol were heated under reflux for 10 hours. After cooling, the product was suction filtered, washed with ether and dried.

Workup

  1. temperatureunder reflux for 10 hours
  2. temperatureAfter cooling
  3. filtrationfiltered
  4. washwashed with ether
  5. customdried

Sources & evidence

ORD record
ord-fcc319077ae3449b8a1b80c24d5f9896
Source dataset
uspto-grants-1990_01
Patent number
US04892576

Reaction notes

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