HCID 178499019, compound → HCID 178499018, compound

HRID 329574Notes

Reaction equation

HRID 329574 reaction equation
C([NH:4][C:5]1[NH:9][N:8]=[C:7]([S:10]([NH:13][C:14]2[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:15]=2[F:21])(=[O:12])=[O:11])[C:6]=1[C:22]([O:24][CH3:25])=[O:23])(=O)C>Cl>[NH2:4][C:5]1[NH:9][N:8]=[C:7]([S:10]([NH:13][C:14]2[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:15]=2[F:21])(=[O:11])=[O:12])[C:6]=1[C:22]([O:24][CH3:25])=[O:23]

Participants

3

Reactant 1

HCID 178499019HCID 178499019, compound

Product 1

HCID 178499018HCID 178499018, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

7.50 g (20 mmol) 5-acetamido-N-(2,6-difluorophenyl)-4-methoxycarbonylpyrazole-3-sulphonamide was suspended in 80 ml 4.4N methanolic hydrochloric acid and heated under reflux for 5 hours. The solvent was distilled and the residue treated with water. The product was suction filtered, washed with water and dried.

Workup

  1. temperatureheated
  2. temperatureunder reflux for 5 hours
  3. distillationThe solvent was distilled
  4. additionthe residue treated with water
  5. filtrationfiltered
  6. washwashed with water
  7. customdried

Sources & evidence

ORD record
ord-cd52f4a14d364a9f81023f698bd4c55e
Source dataset
uspto-grants-1990_01
Patent number
US04892576

Reaction notes

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